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Currently, there is a lack of systematic toxicity evaluation data regarding their systemic effects, and it is urgent to establish an AMPK pathway-dependent toxicity early warning model to ensure the safety of clinical application by assessing the potential effects of natural product metabolites on extrahepatic organs

(More information) Endogenous synthesis and dietary intake provide sufficient coenzyme Q 10 to prevent deficiency in healthy people, although coenzyme Q 10 concentrations in tissues decline with age

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Strenuous exercise causes oxidative stress and muscle damage

10.1002/hep.23276 251